Liverpool is the guest of Southampton in the match of the 17th round in the Premier League.
The Reds are at the top of the league with 33 points, as much as Manchester United and will try to avoid rivals with eventual triumph.
Southampton holds ninth place in the table, but has only seven points less than the first position, so the champion will not have it easy.
We will also see a tactical showdown between coaches Ralph Hasenhuettl and Jurgen Klopp, who have prepared the starting teams for this challenge.
Southampton starting lineup: Forster, Peters, Stephens, Dednarek, Bertrand, Diallo, Ward-Prowse, Armstrong, Djenepo, Ings, Walcott.
Liverpool starting lineup: Alisson, Alexander-Arnold, Fabinho, Henderson, Robertson, Thiago, Wijnaldum, Oxlade-Chamberlain, Mane, Salah, Firmino.